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Monitor Intently (1)pentobarbital will reduce the extent or effect of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or effect of hydrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital will reduce the level or eff